A large number of different factors – genetic and environmental – are involved in causing atopic eczema. One possible trigger of eczema breakouts and skin deterioration is an allergic reaction caused by IgE antibodies. Immunoglobulins E are proteins that defend the body against foreign substances such as parasites.
In atopic people with an overactive immune system, IgE antibodies - as well as triggering hay fever or asthma - may maintain and exacerbate the signs and symptoms of atopic eczema. Adult patients with chronic atopic eczema often have very high IgE levels. The aim of selective immunoadsorption is to remove IgE antibodies by a selective blood filtering process.
A column with a special coating was developed for the purpose which binds these antibodies – and only these antibodies.
Blood is removed continuously from the patient through an arm vein. The blood then passes through a column where the IgE antibodies are captured and collected. After this cleansing process, the blood is directed back into the body through a vein in the crook of the other arm.